Author

Xiao-Feng Lan

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Open access Oct 2026

Data-driven subgroups of adolescent depression: integrating EEG-derived brain networks, childhood trauma, and depressive symptoms

Adolescent major depressive disorder (MDD) is characterized by marked clinical heterogeneity and heightened sensitivity to psychosocial adversity, particularly childhood trauma. Ongoing neurodevelopment and brain plasticity during adolescence may limit the applicability of adult-derived neurobiological models. Pr...

Xuan Liu, Ye-Xian Zeng, Xiao-Feng Lan et al. · BMC Psychology · 0 citations

Open access Oct 2026

Esketamine’s therapeutic effect on anhedonia in adolescents: a post-hoc of a randomized controlled trial

Anhedonia, a prominent symptom of major depressive disorder (MDD), severely impairs patients’ quality of life and is challenging to treat. Although esketamine has shown potential in treating anhedonia in adult treatment-resistant MDD, its effects on adolescents remain under-explored. In this study, a prosp...

Qian-Qian Wu, Wei-Cheng Li, Zhan-Jie Luo et al. · BMC Psychiatry · 0 citations

Aug 2026

Normative Modeling of sgACC-DLPFC Functional Connectivity Identifies a Personalized rTMS Target Associated with Clinical Response in Major Depressive Disorder.

The FCND-guided target framework provides a personalized, mechanism-informed strategy for precision neuromodulation in MDD and is statistically consistent with the hypothesis that distance influences improvement through Z-score normalization in the active group, with a directionally consistent trend in the iTBS dataset...

Zhan-Jie Luo, Wei-Cheng Li, Guanxi Liu et al. · Biological Psychiatry · 0 citations