Aug 2026
ZFP335-MYBL2 transcriptional axis orchestrates Th17 cell differentiation and psoriatic inflammation.
T helper 17 (Th17) cell differentiation is governed by a complex transcriptional network centered on the lineage-specifying factor RORγt, accompanied by STAT3, IRF4, and SMAD2/3. However, the complete repertoire of transcriptional regulators controlling Il17a gene transcription and Th17 commitment remains incompletely...
Wen-Hua Li, Biao Yang, Ning Yuan et al.
· Journal of Immunology · 0 citations