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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

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Xiao-Gan Wang

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Review Open access Aug 2026

The gut microbiota-tryptophan metabolism-immune axis in inflammatory bowel disease: Mechanisms and therapeutic prospects

ABSTRACT The gut microbiota–tryptophan (TRP) metabolism–immune axis is one of the core pathogenic mechanisms in inflammatory bowel disease (IBD). Physiologically, gut microbes convert dietary TRP into bioactive metabolites that regulate intestinal immune balance and barrier function via AHR. In IBD, this axis enters a...

Teng-Fei Wang, Xiao-Gan Wang, Wei-Chen Yuan · 0 citations

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