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Xiaoguang Shi

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Open access Oct 2026

Case Report: A rare case of biopsy-proven lupus nephritis complicated by Graves’ disease in a 39-year-old man

Hyperthyroidism and systemic lupus erythematosus (SLE) are both common diseases in internal medicine. Among them, Graves’ disease (GD) is the most frequent cause of hyperthyroidism, while lupus nephritis (LN) represents one of the most severe organ manifestations of SLE. Basic research suggests that GD and SLE may shar...

Xi-Chang Wang, Xiao-Guang Shi, Bei-Ru Zhang et al. · 0 citations
Open access Aug 2026

Spatial transcriptomic analysis identifies a necroptosis-prone thyroid follicular cell state in Hashimoto’s thyroiditis

This study provides a multimodal characterization of necroptosis in HT, showing that the inflammatory immune microenvironment is associated with TFC loss and activation of an RIPK3-MLKL-predominant necroptosis-related program, without detectable upregulation of total or phosphorylated RIPK1.

Dong-Yu Yang, Cihang Lu, Wei-Ping Teng et al. · 0 citations

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