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Xiao-Guang Yan

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Open access Sep 2026

Impact of frailty phenotype on chronic disease accumulation and healthy life years lost: A multi-state analysis of the UK Biobank

Background Frailty is a systemic vulnerability syndrome linked to adverse health outcomes, yet its role in shaping the dynamic trajectory from health through incident disease to multimorbidity remains poorly understood. Methods Among 276,696 disease-free UK Biobank participants (mean age 55.3 years; 53.5% female; media...

Xiao-Ming Xing, Cong Zhao, Meng-Lin Li et al. · 0 citations

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