Metastatic breast cancer remains a major therapeutic challenge due to the limited efficacy of current treatments against both primary tumors and distant metastases. Here, we developed an arginine-based click-crosslinked nanoplatform for the co-delivery of camptothecin (CPT) and STAT3 siRNA (siSTAT3). The nanoplatform w...
Su-Bin Xiong, Jing-Heng Xiang, Xiao He et al.· International journal of pha...· 0 citations
This review summarizes recent advances in delivery to the lungs, spleen, brain, heart, kidney, bone, and pancreas, discusses major translational bottlenecks, and proposes a direction for predictive design.
Yu Liu, Xiao Guo, Qin Hu et al.· Materials Today Bio· 0 citations
In vitro and in vivo evaluations confirm that R-A/G@Z effectively suppresses aggressive breast tumors while maintaining a good safety profile, offering a promising strategy for intelligent metabolic-chemodynamic cancer nanomedicine.
Nian-Ting Xiao, Xiao He, Da-Xiu Li et al.· Journal of Colloid and Inter...· 0 citations
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