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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

Author

Xiao-Hua Zeng

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2 papers indexed here

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Open access Nov 2026

Single-cell Sequencing Reveals Multi-omics Dynamics During Lymph Node Metastasis in Breast Cancer.

Single-cell sequencing and analysis have advanced our understanding of intra-tumoral heterogeneity for breast cancer lymph node metastasis. However, how alterations at multi-omics levels coordinate together in a single tumor cell to drive metastasis remains unclear. Here we performed single-cell multi-omics sequencing...

Yan Gao, Chao Tang, Xiao-Jing Guo et al. · 0 citations
Open access Sep 2026

A ketogenic enzyme HMGCS2 drives malignant progression in HER2-negative breast cancer via RAB23-mediated β-catenin/TCF signaling and mediates Apatinib resistance.

BACKGROUND 3-hydroxy-3-methylglutaryl-CoA synthase 2 (HMGCS2) is the rate-limiting enzyme of ketogenesis. However, its role in breast cancer progression and drug resistance beyond metabolic regulation remains poorly understood. This study investigates the oncogenic function and resistance-promoting mechanism of HMGCS2...

Jing Wu, Mei Liu, Wei Li et al. · 0 citations

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