Author

Xiao-Hua Zhu

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Aug 2026

A Bifunctional CoFcMOF Nanozyme Enables Dual-Mode PEC-Colorimetric Immunosensing of C-Reactive Protein with Built-In Cross-Validation.

C-reactive protein (CRP), a key inflammatory biomarker, plays a critical role in clinical diagnostics; however, its reliable quantification demands analytical methods that surpass the limitations of conventional single-mode detection by integrating high sensitivity with built-in signal fidelity. Herein, we report a dua...

Lin-Ying Cheng, Yu-Feng Zhong, Man-Qi Li et al. · ACS Sensors · 0 citations

Jul 2026

Revealing the Regulatory Interplay of NHE1 mRNA and Na+ in Cancer Cells Using a DNA Nanosensor.

Two orthogonal gold-nanoparticle-based DNA nanosensors that enable simultaneous imaging of sodium/hydrogen exchanger 1 (NHE1) mRNA and Na+ dynamics in hepatocellular carcinoma cells are reported, providing a molecular tool for decoding ion-based signaling networks in cancer biology.

Ziyu Liu, Lingling Xie, Shuhang Yin et al. · Analytical Chemistry · 0 citations

Aug 2026

Captopril Enables the Inhibition of tRNA-Mediated Tau Aggregation.

Using in vitro reconstitution and high-resolution imaging, tRNA is identified as a major inducer of tau aberrant aggregation and captopril effectively inhibits both general and tRNA-induced tau aggregation, positioning CAP as a potential therapeutic candidate.

Bo-Ru Peng, Quan Deng, Xiao-Hua Zhu et al. · Langmuir · 0 citations