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Author

Xiao-Hui Zhang

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Open access Sep 2026

Guanine promotes acute lung injury by repressing H3K27me3 in sepsis.

The findings reveal that circulating G6PD promotes lung injury by rewiring purine metabolism and remodeling the epigenetic profile in sepsis, shedding light on the critical role of EVs as a pro-inflammatory signal and targeting G6PD for future sepsis diagnosis and treatment.

Chao-Qun Wang, Hui-Juan Wang, Yue-Yu Kong et al. · 0 citations

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