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Sponsored Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt Design Multi-Agent AI Systems Using MCP and A2A: Engineer your own Pyt

Author

Xiaojie Huang

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Open access Sep 2026

Structure-Guided Covalent Design and Biological Evaluation of Glycidamido-Leucinamide Antivirulence Agents Against Pseudomonas aeruginosa

Antimicrobial resistance in Pseudomonas aeruginosa has intensified the need for therapies that do not rely solely on bactericidal activity. Antivirulence agents attenuate pathogenic functions and may complement conventional antibiotics. The elastase LasB is a major quorum-sensing (QS)-controlled virulence factor of P....

Xiao-Qing Mu, Yu-Jing Huang, Hao-Ming Chen et al. · 0 citations
Aug 2026

Structure-Based Discovery of JN210 as a Potent Dual DCN1/HDAC Inhibitor for the Treatment of Nonsmall Cell Lung Cancer.

A dual-targeting strategy aimed at simultaneously inhibiting the oncogenic protein-protein interaction between UBE2M and DCN1, which is critical for neddylation-dependent activation of cullin-RING ligases (CRLs) and histone deacetylase (HDAC) activity is developed.

Tao Zheng, Yi-Gui Li, Yun-Yuan Huang et al. · 0 citations

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