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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Xiaojin Zhang

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2 papers indexed here

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Open access Oct 2026

Spatial and single-nucleus transcriptomics reveals the molecular pathology of type 2 diabetes-associated cognitive dysfunction.

The mechanisms underlying type 2 diabetes-associated cognitive dysfunction (DACD) remain poorly understood, hindering therapeutic progress. Here, we integrated spatial transcriptomics and single-nucleus RNA sequencing to delineate the spatiotemporal molecular and cellular landscape of DACD in brain tissues from 3- and...

Wei Wu, Yu-Meng Yang, Xi-Xi Zhang et al. · 0 citations
Open access Aug 2026

Pharmacologic eIF2B Activation Rescues Neuropathy in CMT2 Subtypes by Normalizing the Integrated Stress Response

This study identifies candidate biomarkers for CMT disease subtypes associated with defects in translational homeostasis and supports eIF2ɑ-ATF4 axis modulation as a promising therapeutic strategy for this disease class.

Mary McMahon, Steve Lianoglou, Sridhar Narayan et al. · 0 citations

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