Xiao-Jun Ren

Biomolecular Condensates Integrate Transcriptional and Epigenetic Responses to Hypoxia

Hypoxia is a defining feature of physiological stress and the core of solid tumors, where aberrant vascularization limits oxygen delivery; cells respond through mechanisms that extend beyond the canonical stabilization of hypoxia-inducible factors (HIFs). Recent studies suggest that hypoxia can promote the formation of...