Author

Xiao-Jun Yu

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Open access Sep 2026

SIRT1/PGC-1α Axis and CPT1A-Mediated Metabolic Reprogramming Reshape Macrophage Polarization to Ameliorate Intervertebral Disc Degeneration.

It is indicated that the SIRT1/PGC-1α/CPT1A axis regulates macrophage polarization through metabolic reprogramming and provides potential therapeutic targets for IDD.

Shan-Xi Wang, Ren-Jie Wang, Kai-Yuan Lin et al. · Pharmacological Research · 0 citations