FDFT1 is associated with ovarian reserve and regulates proliferation and steroidogenesis in the human granulosa cell line KGN via the AKT/mTOR signaling pathway.
Diminished ovarian reserve (DOR) leads to decreased ovarian endocrine function and reduced fertility in women, contributing to infertility. Dysregulated lipid metabolism can impair normal follicular development by interfering with cholesterol metabolism and hormone synthesis, thereby contributing to DOR. Farnesyl-dipho...