Xiao-Liang Gong

Thymine-functionalized bPEI nanocomplexes for synergistic STING activation and PD-L1 silencing to potentiate cancer immunotherapy.

Cancer continues to pose a major global health burden. Although immunotherapy has reshaped treatment strategies, its therapeutic effect is frequently limited by a suppressive tumor microenvironment and systemic toxicity. The stimulator of interferon genes (STING) pathway has emerged as a key target for coordinating inn...