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Xiao-Lin Wang

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Open access Sep 2026

Structural basis for broad orthopoxvirus neutralization by two antibodies targeting distinct L1R epitopes

Two broadly neutralizing monoclonal antibodies, G4 and B9, that target the MPXV M1R protein, homologous to L1R in other OPXVs are presented, demonstrating cross-reactive binding and robust neutralization against multiple pathogenic OPXVs.

Li Chen, Guan-Ying Zhang, Hao-Tian Lin et al. · 0 citations

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