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Xiao-Ling Yang

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Sep 2026

TET1-mediated demethylation of UGT1A1 suppresses neuronal ferroptosis and brain injury in bilirubin encephalopathy.

BACKGROUND Bilirubin encephalopathy (BE) is a severe neurological complication of neonatal hyperbilirubinemia, but the molecular mechanisms underlying bilirubin-induced brain injury remain unclear. We investigated whether UDP-glucuronosyltransferase 1A1 (UGT1A1) regulates neuronal ferroptosis in BE and whether this pro...

Xiao-Ling Yang, Qingmingai Duan, Bei-Bei Lei et al. · 0 citations

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