Xiao-Long Liu

Cascade Catalytic Nanozyme Amplifies Ferroptosis Immunotherapy in Bladder Cancer.

Immune checkpoint inhibitors have shown limited efficacy in bladder cancer due to the immunosuppressive tumor microenvironment. To address this challenge, we developed a β-lapachone-loaded iron-based carbon nanozyme (C-MIL@Lapa) that synergistically induces ferroptosis and immunogenic cell death (ICD). Carbonized MIL-1...