Xiao-Man Yang

From microbiome to outcome: the cascading effects of combining acid suppressants with anti-tuberculosis therapy

Gastrointestinal adverse reactions occur in up to 71.8% of patients receiving anti-tuberculosis drugs (ATDs), and acid-suppressing agents are frequently co-prescribed to alleviate these symptoms. Direct evidence from human studies demonstrates that ATDs alone reduce gut microbial diversity, deplete short-chain fatty ac...