Xiao-Ming Zhao

Necroptosis Activates NLRP3 Inflammasome to Drive Necroinflammation in T-2 Toxin-induced Cartilage Damage.

As a highly toxic mycotoxin present in contaminated food sources, T-2 toxin disrupts skeletal development by inducing cartilage injury. However, the underlying molecular mechanisms remain unclear. Following four weeks of gavage administration of T-2 toxin (200 ng/g body weight/day) to three-week-old male C57BL/6 mice,...