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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Xiaonan Dong

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2 papers indexed here

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Open access Sep 2026

Zinc mediates the allosteric activation of Shiftless to suppress programmed -1 ribosomal frameshifting.

Many medically important viruses, including HIV-1 and severe acute respiratory syndrome coronavirus 2, utilize programmed -1 ribosomal frameshifting (-1 PRF) to synthesize certain proteins essential for the viral life cycle. Shiftless (SHFL) is an interferon-simulated, zinc finger-containing protein that restricts -1 P...

Shi-Ting He, Yong-Feng Zheng, Ru-Hong Ying et al. · 0 citations
Open access Jul 2026

Loss of YY1 in Purkinje cells triggers cerebellar ataxia via Wnt10b-mediated impairment of dendrite development

It is demonstrated that postnatal deletion of Yin Yang 1 (Yy1) in PCs disrupts dendrite and spine formation, impairs synaptic plasticity, and alters protein kinase C gamma (PKCγ) expression, leading to cerebellar ataxia and progressive atrophy.

Lam-Lui Ying, Xiao-Nan Dong, T. C. Leung et al. · 0 citations

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