Author

Xiao-Nan Fang

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Open access Oct 2026

Integrated transcriptomic and metabolomic analyses identify key metabolites and genes in sepsis-associated acute lung injury

Introduction Sepsis-associated acute lung injury (SALI) is a life-threatening pulmonary complication of sepsis with high mortality. This study aimed to prioritize serum metabolites and genes potentially involved in SALI by integrating multi-omics datasets. Methods A rat SALI model treated with Xuanbai Chengqi Decoction...

He Huang, Lei Zhao, Heng Chen et al. · Frontiers in Immunology · 0 citations

Review Open access Nov 2026

Mechanistic roles and therapeutic potential of gut microbiota–neuroimmune crosstalk in the development and progression of Alzheimer's disease

Alzheimer's disease (AD) is a progressive neurodegenerative disorder characterized by cognitive decline and distinct neuropathological and biological alterations, including amyloid-β (Aβ) deposition, tau pathology, synaptic dysfunction, and neuronal loss. Increasing evidence suggests that dysregulated neuroimmune respo...

Xiao-Nan Fang, Ou Xi, Rui Yang et al. · Frontiers in Microbiology · 0 citations