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Author

Xiao-Nan Zheng

2 papers indexed here

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Open access Aug 2026

Asexual Development and Virulence Are Not Affected by Knockout of Five Sexual-Stage Candidate Genes in Toxoplasma gondii

Simple Summary Toxoplasma gondii is a common parasite that infects humans and nearly all birds and mammals, posing a serious threat to immunocompromised individuals and pregnant women, and causing significant economic losses to the livestock industry. Its sexual reproduction occurs exclusively in cat intestines, a poor...

Xing Tian, Cheng Tian, Xin-Sheng Lu et al. · 0 citations
Open access Aug 2026

A Live Attenuated AP2X-1-Deficient Toxoplasma Strain Confers Protective Immunity Against Acute and Chronic Toxoplasmosis in a Murine Model

PruΔap2X-1 represents a potential live-attenuated vaccine candidate against toxoplasmosis, with a favorable safety profile observed under the experimental conditions, and induces a strong Th1-biased cellular and humoral immune response.

Wen-Bo Hao, Li-Xiu Sun, Ru-Shi Tu et al. · 0 citations

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