Gambogic Acid Induces Apoptosis in Raji Lymphoma Cells Via Gfi-1/STAT5 Signaling.
The findings suggest that gambogic acid inhibits the STAT5 pathway by regulating the Gfi-1 gene through promoting apoptosis in Raji cells, suggesting that the anti-cancer mechanism of gambogic acid on Raji cells is influenced by the STAT5 pathway.