Review
Open access
Sep 2026
Biomimetic Scaffold‐Based 3D Models for Decoding Cancer Biology and Advancing Therapy
ABSTRACT While conventional two‐dimensional (2D) cultures and animal models remain essential tools, they frequently fail to recapitulate the three‐dimensional (3D) architecture, biomechanical cues, and spatial complexity of human tumors, thereby limiting their translational relevance. To address these limitations, scaf...
Hai-Tao Zhao, Yue-Chen Han, Jie Li et al.
· Advancement of science · 0 citations