Review
Open access
Aug 2026
Beyond the alarm: unveiling the multifaceted role of IL-33 in kidney disease
Interleukin-33 (IL-33) has long been categorized as a prototypical alarmin released upon cellular injury to initiate Th2-skewed immune responses. However, accumulating evidence from diverse kidney disease models and patient cohorts has unveiled a far more complex and contextually governed functionality. This review syn...
Mei Yang, Su-Ning Miao, Mingli Yu et al.
· Frontiers in Immunology · 0 citations