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Xiao-Tao Shen

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Open access Sep 2026

MAPA: A Semantic Network Framework for Functional Module Discovery and Interpretation in Multi‐Omics Data

ABSTRACT Multi‐omics technologies generate high‐dimensional molecular signatures that provide unprecedented opportunities to uncover biological mechanisms. However, translating complex molecular alterations into coherent and interpretable functional insights remains a major challenge. Existing module discovery methods...

Yi-Fei Ge, Fei-Fan Zhang, Yi-Jiang Liu et al. · 0 citations
Review Open access Aug 2026

The gut microbiome organ

This review synthesizes current mechanistic and translational evidence to conceptualize the gut microbiome as an organ‐like functional system, delineate its structural and functional organization, and propose a framework for mapping, modeling, and therapeutically targeting microbiome‐derived circuits to support precisi...

Yang Bi, Wei-Bin Song, Maria Glymenaki et al. · 0 citations

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