Author

Xiao-Wei Yang

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Sep 2026

LAPTM5 correlates with RPE senescence and subretinal fibrosis through the LAPTM5-WWP2-OPTN mitophagy cascade and cGAS/STING activation in a D-galactose-induced aging model.

Xiao-Wei Yang, Sheng-Lai Zhang, Yan Wang et al. · GeroScience · 0 citations

Aug 2026

Asiaticoside attenuates endothelial cells senescence in diabetic retinopathy via CCND1-mediated mitophagy through the PI3K/AKT/mTOR pathway.

This study is the first to explore the pathological role of CCND1 in DR beyond its classical cell-cycle regulatory function, and reveals that AC attenuates DR progression by alleviating cellular senescence in HMECs by modulating CCND1.

Zhouyang Chen, Yuxin Luo, Xueying Lou et al. · Journal of Ethnopharmacology · 0 citations