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Author

Xiao-Wen Zeng

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Oct 2026

Development of Sex-Specific Physiologically Based Toxicokinetic (PBTK) Models for GenX in Mice and Their Application to Human Health Risk Assessment.

GenX (hexafluoropropylene oxide dimer acid, HFPO-DA), a widely used alternative to perfluorooctanoic acid (PFOA), has raised significant concerns due to its multi-system toxicity and potential human health risks. Accumulating evidence indicates that both the toxicokinetics and toxicity of GenX exhibit marked sex-specif...

Long-Sheng Fan, Jing Zhang, Wen-Hui Zhao et al. · 0 citations
Open access Aug 2026

Prenatal PFAS and longitudinal neurodevelopmental trajectories in preschoolers aged 3-7: effect modification by bile acid metabolism

These findings provide longitudinal evidence on PFAS-related lower neurodevelopment and identify primary conjugated BAs as significant effect modifiers, and the mechanisms underlying this effect modification require further investigation.

Qiong Zhang, Yan-Xi Li, Hua-Lian Chen et al. · 0 citations

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