Author

Xiao-Xiao Tian

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Review Open access Oct 2026

Compartment-specific m7G RNA modification in cancer: mechanisms, tumor adaptation, and therapeutic vulnerabilities

N7-methylguanosine (m 7 G) is distributed across several RNA classes and regulates distinct stages of gene expression. The best-characterized form is the 5′cap of messenger RNA, although m 7 G also occurs in transfer RNA, ribosomal RNA, internal messenger RNA, circular RNA, and transfer RNA-derived small RNAs. Ca...

Xiao-Xiao Tian, Di Huang, Chao Guan · Frontiers in Molecular Biosc... · 0 citations

Review Open access Sep 2026

Spatial proteomics: technical evolution and applications in cancer research

Spatial proteomics is reshaping tissue-based cancer research by linking protein expression to cellular identity, tissue architecture and clinical behavior. Conventional proteomics has provided powerful tools for protein identification and quantification, but most bulk workflows erase the spatial relationships that defi...

Xiao-Xiao Tian, Di Huang, Jia-Xiang Hu · Frontiers in Cell and Develo... · 0 citations