GNG7 attenuates inflammation and modulates macrophage function via the NF-κB/NLRP3 inflammasome pathways in Poly I:C-induced acute lung injury.
Acute lung injury (ALI) is driven by excessive inflammation, but the molecular regulation of macrophage responses remain incompletely defined. This study investigated the role of G protein gamma subunit 7 (GNG7) in mediating inflammatory signaling in cell and mouse models of ALI. RAW264.7 macrophages were stimulated wi...