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Author

Xiao-Xu Huang

2 papers indexed here

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Sep 2026

Asb2-KIF11 Axis Protects Against Heart Failure by Restoring Lysosomal Distribution and Mitochondrial Homeostasis.

BACKGROUND Heart failure remains a leading cause of mortality globally, driven by persistent mitochondrial dysfunction and maladaptive cardiac hypertrophy. Although impaired autophagic flux contributes to cardiac deterioration, the precise molecular mechanisms are still unclear. The ubiquitin-proteasome system serves a...

Yi-Cheng Lv, Zhao Sha, Shi Peng et al. · 0 citations
Open access Aug 2026

Liriodendrin Targets PFKFB3 to Suppress Inflammatory Phenotypic Transition and Vascular Remodeling in Pulmonary Hypertension

Findings reveal that Lidd selectively targets the PFKFB3-mediated glycolytic-epigenetic axis to suppress PASMC phenotypic transformation and pulmonary vascular remodeling, positioning it as a promising therapeutic candidate for PH.

Qing-Ye Zeng, Zhen-Zhen Duan, Qian Liu et al. · 0 citations

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