Lipid Metabolic Reprogramming in Colorectal Cancer: A Central Hub Integrating Diet, Microenvironment, and Therapy Resistance.
Colorectal cancer (CRC), a significant malignancy of the digestive system, represents a considerable threat to global health. Currently, its clinical efficacy is often limited by tumor heterogeneity and therapeutic resistance. Lipid metabolic reprogramming has been identified as a core process in CRC, not only providin...