Author

Xiao-Yan Deng

2 papers indexed here

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Open access Jan 2026

Downregulated Plasma‐Derived Extracellular Vesicle MicroRNAs as Novel Biomarkers for Enhanced Tuberculosis Diagnosis

Background Tuberculosis (TB) remains a leading global cause of infectious disease mortality, while current diagnostic methods face substantial limitations. Extracellular vesicle (EV)–encapsulated microRNAs (miRNAs) demonstrate significant potential as diagnostic biomarkers. This study aimed to evaluate their diagnostic...

Yuheng Liu, Lei Zhang, Yi Yang et al. · Journal of Immunological Res... · 0 citations

Open access Sep 2026

Harmonizing amplification and cleavage kinetics through crRNA scaffold mutation enables robust one-pot CRISPR-Cas12 diagnostics.

CRISPR-based diagnostics (CRISPR-Dx) integrated with isothermal nucleic acid amplification have emerged as a promising strategy for point-of-care molecular testing. Their practical deployment, however, remains constrained by workflow-related limitations. Conventional two-step formats are laborious and highly susceptibl...

Qing-Yang Jiang, Rui-Quan Xu, Zhi-Xin Lin et al. · Proceedings of the National... · 0 citations