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Author

Xiao-Yan Jia

2 papers indexed here

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Open access Aug 2026

Multiplexed Quantification of Variant Abundance in the Globin Gene Family: Integrating Saturation Mutagenesis with Cross-Paralog Prediction

Widespread genetic testing has expanded variant identification, yet functional characterization remains a bottleneck in genome guided medicine. Here, we present a modified Variant Abundance by Massively Parallel Sequencing (VAMP-seq) platform integrating experimental and computational approaches for high-resolution abu...

Xiao-Li Cai, Dao-Yi Wang, Jia-Meng Hu et al. · 0 citations
Open access Aug 2026

Genetic Predisposition and Pharmacological Effects Shape the Divergent Effects of Type 2 Diabetes on Atherosclerosis.

Type 2 diabetes mellitus (T2D) increases the risk of atherosclerotic diseases, including coronary artery disease (CAD), but decreases that for abdominal aortic aneurysm (AAA), forming an intriguing diabetes-atherosclerosis paradox. We investigate how genetic underpinnings and drug effects shape these complex relationsh...

Shu-Fen Zheng, Yonglin Wu, Ai-Jie Li et al. · 0 citations

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