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Sponsored AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI AI AM CLAUDE, A Beginner's Guide: Learn the basics of working with AI

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Xiao-Yan Wang

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Open access Sep 2026

Exploring tumor-derived exosomes as promising antigenic platforms: novel vaccine and immunotherapy strategies for “cold” colorectal cancer

Colorectal cancer (CRC) remains a formidable clinical challenge, largely due to the prevalence of microsatellite-stable tumors characterized by an immunologically “cold” tumor microenvironment (TME) that is resistant to immune checkpoint inhibitors (ICIs). Tumor-derived exosomes (TEXs) play a paradoxical dual role in t...

Xiao-Ting Liu, Xiao-Yan Wang · 0 citations
Open access Sep 2026

Targeting tumor-associated macrophages using mRNA lipid nanoparticles for cytotoxic T lymphocyte–mediated cancer immunotherapy

The immunosuppressive tumor microenvironment (TME) remains one of the main obstacles that limit responsiveness to immunotherapy. Recently, lipid nanoparticles carrying messenger RNA (mRNA) have emerged as a promising strategy to modulate the immunosuppressive TME, with the ultimate goal of sustaining anticancer immunit...

Rui Chen, Letao Xu, Alexander H. Staudacher et al. · 1 citation

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