Open access
Aug 2026
Effects of homozygous PARK7 gene mutations L166P and M26I on BNIP3/BNIP3L interactions and ER-mitochondria proximity
Overall, these findings may reflect altered DJ-1/BNIP3/BNIP3L interaction profiles and BNIP3 sensitive changes in ER-mitochondria proximity associated and global intracellular Ca2+ readouts, particularly in L166P-expressing cells, although direct validation is still required.
Jian-Nan Wu, Kui-Qi Jin, Mengmeng Shen et al.
· Biology Direct · 0 citations