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Author

Xiao-Yong Lei

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Sep 2026

Tangeretin alleviates psoriasis through inhibition of the IL-23/IL-23R signaling pathway.

Psoriasis is a chronic immune-mediated skin disease characterized by strong genetic susceptibility and autoimmune components. Identifying lead compounds from natural products for psoriasis has been proposed as a promising therapeutic strategy. Citri Reticulatae Pericarpium (CRP) is a traditional Chinese medicine materi...

Qing Liu, Jing Liu, Zi-Ren Wang et al. · 0 citations
Jul 2026

Design, Synthesis, and Evaluation of the Novel Benzimidazole Derivatives Inspired YC‐1 as HIF‐1α Inhibitor That Possess Anti‐Colon Cancer Potential

In vivo studies have shown that compound 9o can inhibit tumor growth and reduce the levels of HIF‐1α and glycolysis rate‐limiting enzyme HK2 in HCT‐116 tumor‐bearing mice, and the acute toxicity results also demonstrated the safety of compound 9o in vivo.

Qixian Yang, Jing Zhang, Meijing Liu et al. · 0 citations

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