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Xiao-Yue Li

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Open access Sep 2026

Construction and evaluation of an independently generated transgenic mouse model carrying mutated human HRAS genes for short-term carcinogenicity assessment

The study aimed to construct and evaluate an independently generated transgenic mouse model applied to the short-term carcinogenicity assessment. Mutated human HRAS fragment containing an intron point-mutation was inserted into C57BL/6JGpt mice via bacterial artificial chromosome transgenic technology, eventually gener...

Wen-You Zeng, Yan-Lin Zhang, Xiaoliu Yang et al. · 0 citations

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