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Author

Xiao-Yun He

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Oct 2026

The Transcription Factor PRDM15 Activates the PPP2R5C/PI3K-Akt Pathway to Promote Steroid Hormone Secretion in Goat Granulosa Cells.

The proliferation and steroid hormone production capacity of granulosa cells (GCs) are critical factors in determining follicular maturation and female reproductive success. This study aims to investigate the role of PPP2R5C in regulating GC function and to reveal its upstream transcriptional regulatory mechanisms, the...

Peng Wang, Sen-Xuan Hou, Run-Qing Chi et al. · 0 citations
Open access Aug 2026

A multi-tissue epigenomic atlas links the sheep non-coding genome to domestication and complex traits

Non-coding regulatory variation drives complex traits, domestication, and evolutionary adaptation, yet the sheep genome lacks high-resolution functional annotation. Here we present SheepEpimap, a multi-tissue regulatory atlas harmonizing 516 CUT&Tag histone modifications, ATAC-seq, and RNA-seq datasets across 43 adult...

Zhu Meng, Shiwen Zhang, Zi-Yang Zhuang et al. · 0 citations

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