In situ probiotic-to-postbiotic transformation for spatiotemporally controlled cancer photoimmunotherapy
Current cancer phototherapy is often hindered by suboptimal immunogenicity and inevitable immune escape. Herein, a programmable bio-hybridized phototherapeutic platform is developed by chemical grafting drug-loaded phototherapeutic nano-modules on natural facultative anaerobic probiotics. Exploiting the innate hypoxi...