Open access
Aug 2026
Luteolin-7-O-rutinoside alleviates rheumatoid arthritis through downregulation of the PI3K/AKT/NF-κB and cell cycle signaling pathways
It is demonstrated that lut-7-O-rutin alleviates joint inflammation and synovial hyperplasia in RA may be mediated through inhibiting the PI3K/AKT/NF-κB signaling pathway and downregulating cell cycle-associated proteins, highlighting its potential as a therapeutic agent for RA.
Wei-Xi Liu, Xian Jiang, Shan-Qi Xu et al.
· Frontiers in Pharmacology · 0 citations