Purpose: With the expanding use of therapeutic monoclonal antibodies (mAbs) in inflammatory bowel disease (IBD), there is a critical need for robust, multiplex analytical tools to support therapeutic drug monitoring (TDM) and pharmacokinetic studies. This study aimed to develop and validate a rapid and sensitive liquid...
Yan-Bao Zhang, Na Wang, Wei-Yang Zheng et al.· Drug Design, Development and...· 0 citations
This multi-center, double-blind, placebo-controlled, randomized phase 3 trial (ICWIP) assessed the efficacy and safety of 3-year icotinib adjuvant treatment versus placebo in patients with completely resected stage II-IIIA epidermal growth factor receptor (EGFR) mutated lung adenocarcinoma who had completed four cycles...
Yu-Tao Liu, Le Tang, Xiao-Hong Han et al.· Signal Transduction and Targ...· 0 citations
An innovative, rapid, and highly sensitive HPLC-MS/MS approach for quantifying aficamten concentrations in human plasma and urine is established and critical validation parameters including matrix effects, extraction recovery, carryover, and stability were assessed.
Xiao-Fei Wu, Aijing Liu, Adrienne Griffith et al.· Journal of chromatography. B...· 0 citations
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