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Author

Xiaohua Lu

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Open access Aug 2026

Artemisinin ameliorates rheumatoid arthritis through modulation of the IL-17/PI3K/AKT signaling pathway: integrated network pharmacology, bioinformatics, and experimental validation

Findings suggest that artemisinin may ameliorate RA partly by suppressing IL-17-induced inflammatory activation and PI3K/AKT signaling and PI3K/AKT signaling.

Zong-Yuan Zhou, Le Wang, Yong-Zuo Li et al. · 0 citations
Open access Aug 2026

Discovery of the natural product NAT-6-321056 as a novel modulator of VEGFR2 signaling to suppress tumor angiogenesis.

Virtual screening of 39,442 natural products from the ZINC natural product library, coupled with molecular docking and molecular dynamics simulations to evaluate the binding stability of candidate compounds, identified NAT-6-321056 as a highly promising modulator of VEGFR2 signaling and represents a viable candidate fo...

Xiao Lei, W. Gong, Nadine Wiesmann-Imilowski et al. · 0 citations

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