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Sponsored Artificial Intelligence: A Modern Approach, Global Edition Artificial Intelligence: A Modern Approach, Global Edition

Author

Xiaohui Wu

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Jul 2026

Engineering alanine dehydrogenase to favor nicotinamide cytosine dinucleotide for formate-driven alanine synthesis.

To bypass the availability limitation and metabolic crosstalk associated with native reduced nicotinamide adenine dinucleotide (NADH) pools in L-alanine production, a non-natural cofactor system may offer a compelling strategy to secure independent reducing power. Here, we engineered an alanine dehydrogenase (AlaDH) fr...

Ying-Han Hu, Xiao-Jia Guo, Xue-Ying Wang et al. · 0 citations

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