Open access
Aug 2026
TAL1 is indispensable in ETV2-primed human endothelial cell fate determination
It is demonstrated that ETV2 drives the rapid forward programming of human pluripotent stem cells (hPSCs) into endothelial cells (ECs) by direct remodeling of endothelial-specific enhancers and is established as a master gatekeeper of human EC specification.
Yun Zhao, Mengze Sun, Zi-Xuan Hong et al.
· Science Advances · 0 citations