AI Networking Cookbook: Practical recipes for AI-assisted network automation and development
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Abstract Photoimmunotherapy and RNA interference (RNAi) hold great potential for tumor therapy but exhibit limited efficacy as monotherapies. In this work, we report a red‐light‐activated combinatorial therapy that integrates photodynamic immunotherapy (PIT) with RNAi via a rationally designed photosensitizer, FNBS, de...
Chemotherapy (CT) suffers from poor selectivity and systemic toxicity, while photodynamic therapy (PDT) and photothermal therapy (PTT) are inherently limited by tumor hypoxia and thermoresistance. Herein, we develop a trimodal synergistic nanoplatform (PDM‐BDP NPs) for ovarian cancer treatment by integrating PDT, mild...
Idiopathic pulmonary fibrosis (IPF) is a progressive refractory lung disorder with limited effective therapies. Although RNA interference (RNAi) holds promise for IPF treatment, current delivery systems are hampered by complex preparation, redundant components, and an inability to modulate oxidative stress, which sever...
This work helps to transform PSs from ROS-dependent killing agents into therapeutics with orthogonal antibacterial mechanisms, establishing a proof-of-concept for a generalizable PSs design paradigm.
A triple‐stage precision nanogel platform in which carbon dots serve as organelle‑targeted delivery vehicles that achieved over 85% tumor growth inhibition with minimal systemic toxicity and offers a promising strategy to overcome key barriers in cancer therapy.
This work provides an oxygen-unrestricted synergistic strategy to compensate for the limitations of standalone Type II PSs or HAPs monotherapy, offering valuable insights for clinical cancer treatment.
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