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Sponsored AI Networking Cookbook: Practical recipes for AI-assisted network automation and development AI Networking Cookbook: Practical recipes for AI-assisted network automation and development

Author

Xiaole Han

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Sep 2026

Input-Triggered Allosteric Activation of CRISPR-Cas12a by Modular Loop-Engineered Hairpins.

Achieving precise control over CRISPR-Cas12a activity remains a fundamental challenge in the development of versatile sensing platforms, particularly for applications in diagnostics. Herein, we report an allosteric strategy that employs modular loop-engineered hairpin (MLEH) to precisely control Cas12a activation, ther...

N. Yin, Li Zhang, Rui-Ling Lu et al. · 0 citations
Open access Jul 2026

A structural accessibility principle for LbuCas13a activation by noncontiguous DNA

It is shown that activation occurs only when overhang positioning creates an accessible protein–DNA interface, and a structural accessibility principle for LbuCas13a activation by noncontiguous DNA is defined.

Wei-Tao Wang, Yu-Han Chen, Ziyun Li et al. · 0 citations

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