Review
Open access
Aug 2026
Role of STX1A in Parkinson’s disease: evidence, mechanistic hypotheses, and translational perspectives
The biomarker and therapeutic potential of STX1A remains preliminary because diagnostic performance, disease specificity, longitudinal stability, and causal relevance have not been adequately validated and future studies using cell-type-specific STX1A manipulation, rescue experiments, electrophysiology, and multicenter longitudinal cohorts are required to define the biological and clinical significance of STX1A in PD.
Rui Xu, Rui Li, Hongmei Li et al.
· Frontiers in Aging Neuroscie... · 0 citations