Author

Xiaolin Sun

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Aug 2026

Metabolic-reprogrammed MnO₂-Mg/Pt@BBF nanozyme disrupts biofilm cohesion for enhanced chemodynamic therapy of periodontitis.

OBJECTIVES To overcome the intrinsic incompatibility between dense periodontal biofilms and chemodynamic therapy (CDT), we developed a vacancy-engineered MnO₂ nanozyme that integrates redox-state programming, Mg²⁺-enabled endogenous H₂O₂ amplification, and covalently immobilized quorum-sensing inhibition for the local...

Meng Bo, Jiao Fang, Yu-Ning Wu et al. · Dental Materials · 0 citations

Aug 2026

A proton-gated gold nanocluster platform for disrupting biofilm bioenergetics and suppressing virulence in bacterial infections.

This strategy demonstrates that targeting intracellular energy vulnerabilities can achieve antibacterial, antibacterial, antibiofilm, and antivirulence effects against persistent infections.

Jia Liu, Xiaolin Sun, Jing Zhou et al. · Biomaterials · 0 citations

Review Open access Aug 2026

Piezoelectric Nanocoatings on Bio-Interfaces: Microenvironment Remodeling, Biofilm Disruption, and Immunomodulatory Integration

This review evaluates the material design principles and classifications of inorganic, organic, and hybrid piezoelectric nanocoatings and detail their multifaceted antibacterial mechanisms and trace their therapeutic potential in orthopedic and dental implants, as well as wound management.

Yue-Meng Li, Li-Xin Tang, Peng-Fei Gao et al. · Microorganisms · 0 citations